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Updated: May 10, 2025

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
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一个离散的重叠分辨算法 (DORA),用于解决微生物个体模型中的空间重叠.

Ihab Hashem1, Jian Wang1, Jan F M Van Impe1

  • 1KU Leuven, Chemical Engineering Department, BioTeC & OPTEC, Ghent, Belgium.

PLoS computational biology
|April 21, 2025
PubMed
概括

针对微生物生长的基于个体的建模 (IbM) 是计算密集的. 一个新的离散重叠分辨算法 (DORA) 显著提高了模拟大微生物群体的效率.

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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
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