肠-大脑神经调节剂在刺激性肠综合征中的有效性:更新的系统性审查和元分析

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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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Mais Khasawneh1, Marjan Mokhtare2, Paul Moayyedi3

  • 1Leeds Gastroenterology Institute, St James's University Hospital, Leeds, UK; Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.

The lancet. Gastroenterology & hepatology
|April 21, 2025
PubMed
概括

肠-大脑神经调节剂,特别是三环抗抑郁药 (TCA),有效地减少刺激性肠综合征 (IBS) 症状和腹痛. 虽然TCA显示了最强有力的证据,但选择性血清素再吸收抑制剂 (SSRI) 也可能有利于IBS患者的疼痛管理.

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