在二次预防中,LDL胆固醇水平和降脂疗法. 来自BRING-UP未来注册表的基准数据
Furio Colivicchi1, Gianna Fabbri2, Fabrizio Oliva3
1Clinical and Rehabilitation Cardiology Department, San Filippo Neri Hospital, ASL Roma 1, Roma, Italy.
International journal of cardiology
|April 21, 2025
概括
这项研究突出了实现心血管预防目标的差距,许多患者没有达到LDL胆固醇或血压目标. 教育干预旨在改善临床实践中的二次心血管预防.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 临床研究 临床研究
背景情况:
- 在临床实践中,二次心血管预防指南并不总是得到一致的满足.
- 一个国家项目旨在通过教育和数据收集来弥合这一差距.
- 动脉血栓事件需要改进患者管理策略.
研究的目的:
- 评估二次心血管预防教育干预措施的有效性.
- 评估基线临床特征和风险因素控制在患有动脉血栓事件的患者.
- 为了识别对脂质和血压管理的指南遵守的差距.
主要方法:
- 这是一项观察性,前性,多中心研究 (BRING-UP预防).
- 涉及教育干预,然后在3,6个月和12个月收集数据.
- 从189个心脏病中心招募了4790名患有动脉血事件的患者.
主要成果:
- 32.6%的患者达到LDL胆固醇<55 mg/dL;39.2%达到血压目标.
- 达他林的处方从69%增加到96%; 74.5%接受了达他林-ezetimibe组合.
- 不经常使用PCSK9抑制剂或inclisiran.
结论:
- 很大一部分患者没有达到LDL胆固醇或血压目标.
- 该研究提供了关于二次预防中风险因素管理的基线数据.
- 进一步的后续行动将评估干预措施对可修改风险因素的影响.
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