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对饮用水中抗性真菌的评估方法进行比较

Yihan Wang¹, Gehui Wu¹, Qiqi Wan¹

¹Key Laboratory of Northwest Water Resource, Environment and Ecology, MOE, Xi'an University of Architecture and Technology, Xi'an, 710055, China; Shaanxi Key Laboratory of Environmental Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China.

Environmental research

|April 21, 2025

概括

菌类对饮用水中的有很强的抵抗力. 这项研究推度-时间 (CT) 方法来评估真菌耐药性,并确定细胞壁成分,抗氧化剂和生物膜作为关键的耐药性机制.

科学领域:

环境微生物学环境微生物学
水处理技术水处理技术.
菌类学菌类学是指菌类学.

背景情况:

由于高耐药性,真菌病原体在饮用水中存在重大风险.
目前评估真菌耐药性的方法不足,缺乏标准化和实时功能.
了解耐药机制对于水系统中有效的真菌控制至关重要.

研究的目的:

系统地比较评估真菌耐药性的方法:日志减少,度-时间 (CT) 值和最小抑制度 (MIC).
确定有助于真菌抵抗消毒的关键机制.
建议评估真菌耐药性的最有效方法.

主要方法:

对日志减少,CT值和MIC方法进行比较分析,以评估真菌的耐药性.
研究真菌细胞壁的成分 (黑色素,奇托),抗氧化系统和生物膜的形成.
在消毒动态中对消毒剂衰变,接触时间和实验条件的评估.

主要成果:

由于其动态和全面的性质,CT值方法被推为评估真菌耐药性的最有效方法.
真菌细胞壁的组成 (黑色素,奇托),抗氧化酶和生物膜的形成显著增强了的耐药性.
日志缩减侧重于终点无活化,而MIC则提供了回顾性评估.

结论:

CT方法为评估水处理中的真菌耐药性提供了一个优越的框架.
了解耐药机制对于制定针对性策略来对抗真菌污染至关重要.
需要标准化方法和改进的控制策略来解决饮用水中的真菌风险.

关键词:

耐性耐性耐性耐性抗机制抗的机制评估方法评估方法菌的真菌是一种.

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