泰国第三级护理机构二十年来感染性内心炎的趋势
Natnicha Pongbangli1, Romanee Chaiwarith2, Arintaya Phrommintikul3
1Division of Cardiology, Department of Internal Medicine, Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand.
泰国的传染性内心炎 (IE) 显示患者人口老龄化和伴随性疾病的增加. 尽管治疗取得了进展,但死亡率仍然很高,这凸显了管理这种严重的心脏感染的持续挑战.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 传染性内心炎 (IE) 具有显著的发病率和死亡率.
- 了解流行病学转变对于有效管理至关重要.
研究的目的:
- 分析泰国IE患者随着时间的推移而发生的临床特征,微生物学和结果的变化.
- 为了确定IE患者人口统计,并发症和治疗策略的趋势.
主要方法:
- 在三个时期 (1998-2001,2012-2015,2016-2020) 中,对435名IE患者进行了回顾性队列研究.
- 对临床数据,微生物学资料和治疗结果的分析.
- 对不同时间段的患者特征和结果进行统计比较.
主要成果:
- 患者的中位年龄显著增加 (42至58岁).
- 风湿性心脏病的患病率下降,同时伴随疾病的患病率增加.
- 我国菌株 (Streptococcus suis) 成为一个显著的病原体;培养负的IE率下降.
- 手术干预率上升,但住院死亡率保持稳定,为18.6%.
结论:
- 泰国的IE流行病学正在演变,老年患者人口统计和伴随疾病正在发生变化.
- 尽管诊断得到了改进,手术干预增加,但IE的死亡率仍然是一个重大挑战.
- 需要有针对性的战略来解决与传染性内心炎相关的持续高死亡率.
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