抑郁症中阻塞性睡眠呼吸暂停的患病率和危险因素:一项观察性回顾性研究
Xiujuan Chen1, Zhengfa Qiu1, Changzhou Hu1
1Department of Psychiatry, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, Zhejiang, China.
Frontiers in psychiatry
|April 22, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 在抑郁症患者中很常见,影响31.4%的患者. 关键的危险因素包括男性性别,年龄较大,肥胖和高的LDL-C,这突显了抑郁症患者需要进行OSA查的必要性.
科学领域:
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
- 心脏病学 心脏病学
背景情况:
- 以前的研究集中在阻塞性睡眠呼吸暂停 (OSA) 患者的抑郁症.
- 对抑郁症患者OSA患病率的研究是有限的.
- 这项研究旨在确定抑郁症患者的OSA患病率和相关风险因素.
研究的目的:
- 确定患有抑郁症的个体中阻塞性睡眠呼吸暂停 (OSA) 的患病率.
- 在这个患者群体中确定与OSA相关的特定风险因素.
主要方法:
- 一年内经过多睡眠图 (PSG) 的抑郁症患者的回顾性图表审查.
- 患者被分为OSA (呼吸暂停-呼吸暂停指数 (AHI) ≥5) 和非OSA组.
- 使用PSG数据分析睡眠结构和风险因素.
主要成果:
- 31.4%的抑郁症患者患有OSA.
- OSA和非OSA组之间的显著差异包括性别,BMI,吸烟和脂质水平 (p<0.05).
- OSA患者的N3睡眠持续时间和百分比减少,觉醒增加,兴奋指数更高,氧化水平较差 (p<0.01).
结论:
- 阻塞性睡眠呼吸暂停 (OSA) 在抑郁症患者中很普遍.
- 在这个群体中,OSA的危险因素包括男性性别,晚年,BMI≥25.0 kg/m2,以及升高的LDL-C.
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