Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

Correction to "Cell-Penetrating and Enzyme-Responsive Peptides for Targeted Cancer Therapy: Role of Arginine Residue Length on Cell Penetration and In Vivo Systemic Toxicity".

ACS applied materials & interfaces·2026

Same author

High mannose content of mesenchymal glioblastoma correlates with hydroxyl proton transfer-weighted (HPTw) MRI as noninvasive biomarker of tumor aggressiveness.

Science advances·2026

Same author

Whole-body in vivo MPI cytometry reveals injection route-, dose-, cell size-, and disease-dependent differences in organ distribution.

Science advances·2026

Same author

Stepwise Purification of Superparamagnetic Iron Oxide Nanoparticles Improves Magnetic Particle Imaging Performance.

Nano letters·2026

Same author

MPI-Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers.

Advanced functional materials·2026

Same author

Detection of Aggressive Mesenchymal Glioblastoma by Mannose-Weighted CEST MRI.

bioRxiv : the preprint server for biology·2026

Search research articles

相关实验视频

Updated: May 10, 2025

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

Published on: July 2, 2020

用磁纳米粒子进行成像引导的精密超热.

Ali Shakeri-Zadeh^1,2, Jeff W M Bulte^1,2,3,4,5,6

¹The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Nature reviews bioengineering

|April 22, 2025

概括

磁纳米粒子使得精确的,图像导向的癌症高温. 这种方法可以进行动态的治疗调整,改善瘤向和尽量减少对健康组织的损害.

更多相关视频

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

相关实验视频

Last Updated: May 10, 2025

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System

Published on: July 2, 2020

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
在瘤学瘤学.

背景情况:

磁纳米颗粒,特别是超偏磁铁氧化物 (SPIO),被用于先进的医学成像和治疗应用.
检测这些纳米粒子的体内成像模式包括MRI,MPI,MMUS和MPAI.

研究的目的:

探索磁纳米粒子介导成像和磁流体高温 (MFH) 的协同潜力,用于精确的瘤治疗.
讨论将成像指导型MFH转化为临床实践的要求.

主要方法:

对现有的磁纳米粒子成像技术 (MRI,MPI,MMUS,MPAI) 的审查.
基于实时成像数据的纳米粒子加热条件的动态调制分析.
使用生物分布和热剂量信息,探索个性化治疗规划.

主要成果:

临床前数据表明,在治疗期间,纳米粒子加热的动态调制是可行的.
图像引导的MFH提供了选择性瘤加热的潜力,同时不影响健康组织.
个性化治疗计划可以根据成像衍生的纳米粒子和热剂量分布来制定.

结论:

将磁纳米粒子成像与MFH相结合,为向癌症治疗提供了一个有前途的战略.
临床翻译需要开发安全,有效的纳米粒子和集成成像-加热平台.
需要进一步的研究,以优化纳米粒子配方和硬件集成,用于临床应用.