在急性初级角关闭患者的白内障手术期间检测到隐藏的区域性病变:一项回顾性研究
Jiawei Chen1,2,3, Xiang-Ling Yuan1,4, Xinyue Zhang1,2
1Aier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.
PeerJ
|April 22, 2025
概括
隐形区域病变是一种影响眼睛透镜支的疾病,与急性初级角度闭合 (APAC) 密切相关. 这一发现表明,区域病变可能是发展亚太地区的关键风险因素.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 解剖病理学 解剖病理学
背景情况:
- 在急性初级角关闭 (APAC) 的发展中隐藏性区域病变的作用尚不清楚.
- 这项研究探讨了隐藏性区域病变和亚太地区之间的关联.
研究的目的:
- 为了确定在白内障手术期间检测到的隐藏性区域病变与APAC之间的关联.
- 调查亚太地区有或没有隐性区域病变的患者的生物识别特征.
主要方法:
- 一项追溯病例控制研究,涉及27名中国单方面亚太地区患者和132名对照.
- 在白内障手术期间发现了隐藏性区域病变;其比例在不同组之间进行了比较.
- 多变量后勤分析评估了隐性区域病变和APAC之间的关联,以及眼部生物识别参数.
主要成果:
- 与对照组相比,亚太地区的患者 (63.0%) 发现隐性区域病变的比例显著更高 (1.5%,P < 0.001).
- 隐性区域病变与APAC有很强的关联 (OR = 126.49,P < 0.001),即使对轴长度和性别进行了调整.
- 与相反的眼睛相比,APAC眼睛,有或没有隐性区域病变,表现出较浅的前腔深度和更前的透镜定位.
结论:
- 隐藏性区域病变的更高患病率与亚太地区显著相关.
- 隐藏性区域病变可能是亚太地区的危险因素,可能会导致前镜片的移位.
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