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相关概念视频

Enzyme Inhibition01:30

Enzyme Inhibition

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Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.
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Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

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The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
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Protecting Groups for Aldehydes and Ketones: Introduction01:23

Protecting Groups for Aldehydes and Ketones: Introduction

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Protecting groups are compounds that can bind to a specific functional group in the presence of other functional groups to protect them from undesired chemical reactions. These compounds can selectively bind to particular functional groups and advance chemoselective reactions in polyfunctional systems (Figure 1). After the functional group has served its purpose, it is removed by reacting it with specific compounds.
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iChip01:24

iChip

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The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...
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Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
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在有图案的环境中对活性合物进行封闭和调节的封闭.

Carolina van Baalen1, Stefania Ketzetzi1, Anushka Tintor1

  • 1Laboratory for Soft Materials and Interfaces, Department of Materials, ETH Zürich, Vladimir-Prelog-Weg 5, 8093 Zürich, Switzerland. lucio.isa@mat.ethz.ch.

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研究人员设计了活性体颗粒,以通过与有模式的障碍物产生排斥性相互作用,避免在边界积累. 调节电场频率精确控制障碍物大小,使这些粒子能够进行可调节的限制和组织.

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科学领域:

  • 软物质物理学 软物质物理学
  • 结合体科学 结合体科学
  • 活动物质 活动物质

背景情况:

  • 活跃的体颗粒倾向于在边界积聚.
  • 控制界面上的粒子行为对于各种应用至关重要.

研究的目的:

  • 为了设计能够避免边界积累的活性体颗粒.
  • 开发一种可调节的限制和组织活性颗粒的方法.

主要方法:

  • 自行驱动的合体和有图案的障碍物之间的工程远程排斥相互作用.
  • 利用电场来控制粒子与障碍物的相互作用.
  • 调节应用场频率以调整有效障碍尺寸.

主要成果:

  • 粒子成功地避免了由于工程排斥相互作用而在障碍物上的积累.
  • 应用的场频精确控制了有效的障碍物大小和粒子接近距离.
  • 实现了可调节的门和封闭,允许在障碍物之间控制进入区域.

结论:

  • 开发的方法提供了对活性颗粒的限制和组织的多功能控制.
  • 这种方法可以在粒子分类和活性颗粒的按需定位方面有潜在的应用.