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Updated: May 10, 2025

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根据其质谱指纹识别植物用超高性能液体染色学-质谱学识别植物

Akhilesh Kumar^1,2, Dipak Kumar Mishra^1,2, Sanjeev Kanojiya^1,2

¹Sophisticated Analytical Instrument Facility & Research, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.

Journal of mass spectrometry : JMS

|April 22, 2025

概括

基于质谱的方法通过其化学完整性准确地识别植物原料,达到100%的准确性. 这种方法克服了植物医学质量控制传统方法的局限性.

科学领域:

药理学是指药理学,即药理学是指药理学.
分析化学分析化学
代谢学代谢学代谢学

背景情况:

传统的植物识别方法 (形态分类学,显微镜,DNA条形码) 缺乏化学完整性评估.
植物原料的质量对于草药的有效性和安全性至关重要.
需要强大的方法来确保植物的化学真实性.

研究的目的:

根据化学完整性开发和验证基于质谱的方法,以识别基于化学完整性的植物原料.
通过质谱指纹分析 (MSFP) 来确定精确植物识别的关键值.
评估方法的准确性,选择性和稳定性,以应对变化.

主要方法:

为样本准备和质谱指纹 (MSFP) 搜索制定了标准化操作程序 (SOP).
使用质谱法分析了30种植物物种.
标志着与参考光谱相似的MS1得分被用作首要识别指标.

主要成果:

质谱法在识别30种植物物种方面实现了100%的准确性和选择性.
超过50%的MS1得分被确定为基于化学完整性准确识别的门.
该方法证明了对季节和地理变化的稳定性,MS1的得分变化不到15%.

结论:

基于质谱的MSFP分析提供了一种可靠和准确的方法,可以根据其独特的化学配置来识别植物性物质.
这种技术通过确保原材料的化学完整性来加强植物性药物的质量控制.
化学条形码的开发进一步验证了识别过程,确保了可靠的植物认证.

关键词:

植物植物的植物.化学条形码化学条形码化学指纹的使用数字图书馆数字图书馆数字图书馆质谱指纹的指纹

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