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Updated: Jun 16, 2025

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通过考虑变异基质特异性和新型多态单体类型,改善了对CYP2D6催化药物代谢的预测

Inger Johansson1, Emmanouella M Xanthopoulou1, Yitian Zhou1,2

  • 1Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

Clinical pharmacology and therapeutics
|April 22, 2025
PubMed
概括

酶CYP2D6的遗传变异显著影响药物代谢. 确定了新的多态单体类型,提高了对RISPERIDONE和DESMETHYLTAMOXIFEN等药物的预测准确度.

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