Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

No-cost envelope modification improves fecal immunochemical test laboratory acceptance in a US Veterans Affairs colorectal cancer screening trial.

Journal of medical screening·2026
Same author

Non-communicable disease care for persons living with HIV in Peru: A national physician cross-sectional study.

PLOS global public health·2025
Same author

Efficacy and Safety of Fecal Microbiota Transplant for Prevention of Recurrent Clostridioides difficile Infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2025
Same author

Monitoring and reporting adverse events in pragmatic clinical trials testing nonpharmacological pain management interventions.

Pain medicine (Malden, Mass.)·2024
Same author

How Healthcare Systems Negatively Impact Environmental Health? The Need for Institutional Commitment to Reduce the Ecological Footprint of Medical Services.

Epidemiologia (Basel, Switzerland)·2023
Same author

A digital health game to prevent opioid misuse and promote mental health in adolescents in school-based health settings: Protocol for the PlaySmart game randomized controlled trial.

PloS one·2023

相关实验视频

Updated: Jun 9, 2026

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

2.8K

CoVimmune COVID-19免疫计算器:网络应用程序开发和验证研究

Rebecca Slotkin1, Tassos C Kyriakides2,3, Vinni Yu4

  • 1Department of Medicine, Yale School of Medicine, 950 Campbell Ave, Bldg 1, Floor 5, West Haven, CT, 06516, United States, 1 2038005320.

JMIR formative research
|April 22, 2025
PubMed
概括

一个新的网络工具从疫苗接种成人的血清免疫球蛋白G (IgG) 水平估计了SARS-CoV-2中和抗体 (nAb) 标位. 这个计算器有助于评估疫苗诱导的对COVID-19的保护.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.免疫力是一种免疫力.免疫球体蛋白G 免疫球体蛋白G中和抗体的抗体中和.以患者为中心的护理.接种疫苗 接种疫苗疫苗的犹 疫苗的犹接种疫苗的时间安排网络应用程序 网络应用程序

更多相关视频

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses
05:49

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses

Published on: November 21, 2023

1.5K
Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
06:08

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

1.0K

相关实验视频

Last Updated: Jun 9, 2026

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

2.8K
Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses
05:49

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses

Published on: November 21, 2023

1.5K
Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
06:08

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

1.0K

科学领域:

  • 免疫学 免疫学 免疫学
  • 传染性疾病 传染性疾病
  • 公共卫生 公共卫生

背景情况:

  • 研究血清抗SARS-CoV-2S1/受体结合域免疫球蛋白G (IgG) 和中和抗体 (nAb) 标位之间的相关性.
  • 在美国成年人群中,在接种疫苗后的不同时间点分析nAb标位.

研究的目的:

  • 开发一种可访问的基于网络的计算器,以使用商业抗SARS-CoV-2血清IgG结果近似估计SARS-CoV-2中和能力.
  • 为预测nAb标位提供以患者为中心的工具.

主要方法:

  • 利用两个已发表的数据集:一个显示IgG-nAb相关性,另一个跟踪疫苗接种后的nAb标位.
  • 从线性回归模型中纳入了统计学上显著的临床因素,预测了从IgG.到nAb的IgG.
  • 开发了一个公开可用的网络应用程序,用于用户输入血清IgG值.

主要成果:

  • 该应用程序根据用户提供的血清IgG值提供了估计的nAb标位.
  • 估计的nAb标位与理论的疫苗介导抗体保护水平相联系.
  • 显著影响IgG对nAb的预测的临床变量被用于以患者为中心的预测.

结论:

  • 开发的应用程序将保护性抗体的科学研究与临床实践联系起来.
  • 为评估疫苗诱导的针对SARS-CoV-2的免疫力提供了一个实用的工具.
  • 展示了基于Web的应用程序在将免疫学研究成果转化为临床用途方面的潜力.