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Updated: May 10, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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创新的肉瘤疗法使用多方面的纳米-PROTAC诱导的EZH2降解和免疫增强增强免疫力

Zhihao Chen1, Yi Tai2, Chuangzhong Deng1

  • 1Department of Musculoskeletal Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou, 510060, PR China.

Biomaterials
|April 22, 2025
PubMed
概括

研究人员开发了YM@VBM,一种新的纳米PROTAC,以向肉瘤中的EZH2. 这种创新疗法降解了EZH2,激活了抗瘤免疫力,并提供了一种有前途的新型肉瘤治疗方法.

关键词:
在 EZH2 中使用.免疫系统的激活纳米酶纳米酶是一种纳米酶.这就是PROTAC.光热疗法是一种光热疗法.

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