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Updated: May 10, 2025

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

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在同一个单细胞中对染色质可访问性和基因表达的联合分析揭示了癌症特异性调节程序

Lei Tang1, Jinsong Zhang1, Yanqiu Shao1

  • 1State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.

Cell systems
|April 22, 2025
PubMed
概括

平行-seq同时测量单细胞中的染色质可访问性和基因表达. 这种具有成本效益的技术揭示了导致癌症进展的遗传和表观遗传因素,并确定了潜在的治疗点.

关键词:
在表观基因组学上,表观基因组学.调节基因表达 调节基因表达肺癌是一种肺癌.单细胞多组体的多组体.

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