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Updated: Jun 13, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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了解遗传编码的标签和拥挤剂如何影响异染色蛋白HP1α的相分离

Ziling Kate Zhou1, Kibeom Hong2, Bo Huang3

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell reports methods
|April 22, 2025
PubMed
概括

像GFP这样的基因编码的光标签可以抑制异色素蛋白1α (HP1α) 的相分离. 一个小的UnaG标签最小地扰乱HP1α相分离,使细胞可视化.

关键词:
科普:分子生物学 分子生物学基因编码的光标签异性染色蛋白蛋白质 1 异性染色蛋白质 1液态-液态相隔离方法 液态相隔离方法显微镜 显微镜是指使用显微镜.

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