核心等级1:核心等级方法的概述
Gordon Guyatt1,2,3,4, Thomas Agoritsas5,3,6,4, Romina Brignardello-Petersen5
1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada guyatt@mcmaster.ca.
概括
这篇文章介绍了评估证据和提出建议的GRADE方法. 它详细介绍了PICO用于问题制定,并讨论了临床指导的证据确定性.
科学领域:
- 卫生科学 卫生科学 卫生科学
- 基于证据的医学基于证据的医学.
- 临床实践指南 临床实践指南
背景情况:
- 在系统性审查和准则制定中,GRADE (建议评估,开发和评估的分级) 方法被广泛使用.
- 评级指南已经发展,需要清楚地介绍其核心组件.
研究的目的:
- 提供GRADE方法的基本元素的概述.
- 专注于对比证据进行总结和提出建议所需的核心判断.
- 介绍一系列关于核心等级必需品的文章中的第一篇.
主要方法:
- 使用PICO (人口,干预,比较,结果) 结构制定临床问题的详细指南.
- 改进问题以考虑跨患者群体的效果修饰者.
- 概述GRADE的核心判断,包括证据确定性和从证据转向建议.
主要成果:
- 介绍了使用PICO构建问题的结构化方法.
- 强调在影响估计中考虑患者异质性的重要性.
- 概述了Core GRADE方法的后续步骤,用于证据综合和指导方针开发.
结论:
- 格雷德方法为医疗保健中的基于证据的决策提供了一个强大的框架.
- 有效地提出问题和评估证据确定性对于制定可靠的临床建议至关重要.
- 这篇文章是对核心等级方法的基本介绍.
相关概念视频
Fundamentals of Nursing Process I
4.8K
The nursing process is the core of practice for every registered nurse to deliver holistic, patient-focused care. The following are the five steps in the nursing process.
4.8K
Basic Concept
700
Engineering mechanics is a branch of engineering that studies motion and the forces acting on objects. It is a fundamental subject and forms the basis of many other engineering disciplines. Length, time, mass, and force are some basic concepts in engineering mechanics.
Length, which measures the distance traveled by an object, is a fundamental concept in engineering mechanics. We use coordinates relative to a reference point to describe the distance. Length not only helps to describe the...
Length, which measures the distance traveled by an object, is a fundamental concept in engineering mechanics. We use coordinates relative to a reference point to describe the distance. Length not only helps to describe the...
700
Types of Aggregate Grading
358
Aggregate grading is crucial in economically obtaining a concrete mix with adequate strength, reasonable workability, and minimal segregation. There are four types of aggregate gradation: well-graded, uniformly (or one-sized) graded, gap-graded, and open-graded.
Well-graded aggregates include a complete range of necessary size fractions that fit together to create a dense matrix with minimal voids, represented by a smooth, continuous gradation curve. This type of grading ensures good...
Well-graded aggregates include a complete range of necessary size fractions that fit together to create a dense matrix with minimal voids, represented by a smooth, continuous gradation curve. This type of grading ensures good...
358
Introduction to Developmental Psychology
98
Developmental psychology explores the changes and continuities in human abilities throughout life, encompassing physical, cognitive, linguistic, and social dimensions. Human development is not restricted to growth, but includes aspects of decline, particularly in physical abilities as individuals age. Developmental psychologists seek to understand how people change as they age and how their mental and social skills evolve.
Developmental Milestones
A key concept in developmental psychology is...
Developmental Milestones
A key concept in developmental psychology is...
98
The Nativist Approach
29
The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
29
Information Processing Approach
23
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
23


