植物疗法治疗下尿道症状:当前的位置和未满足的需求
Juan Justo Quintas1, Stavros Gravas2
1Department of Urology, HM Hospitales, Madrid, Spain; ROC Clinic, Madrid, Spain; HM Hospitales Faculty of Health Sciences, University Camilo José Cela, Madrid, Spain.
European urology focus
|April 22, 2025
概括
植物疗法为下泌尿道症状 (LUTS) 提供了一个替代方案. 尽管目前有一些指导方针,但需要更多的研究来制定基于证据的建议,用于管理LUTS中的植物提取物.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学是指药理学,即药理学是指药理学.
- 基于证据的医学是基于证据的医学.
背景情况:
- 植物疗法正在作为治疗下泌尿道症状 (LUTS) 的传统医疗疗法的替代方案进行探索.
- 研究结果的变化和有限的监管监督阻碍了对植物治疗药物的基于证据的建议的制定.
- 目前,Hexanic Serenoa repens是欧洲泌尿病学协会推用于男性LUTS的唯一植物治疗剂.
研究的目的:
- 审查目前植物疗法管理下泌尿道症状 (LUTS) 的现状.
- 确定LUTS管理中的研究缺口和植物提取物的未来需求.
- 为LUTS.植物性产品的常规临床使用提供见解.
主要方法:
- 对LUTS植物疗法的现有文献进行小型综述.
- 对植物提取物的现有证据和监管状况进行分析.
- 确定当前研究和临床应用的局限性.
主要成果:
- 对LUTS的植物治疗药物的使用广泛,但缺乏可靠的比较数据.
- 关于植物提取物研究的质量和研究结果存在显著的差异 LUTS.
- 赫克萨尼克 (Hexanic Serenoa repens) 有一个具体的建议,但对于其他植物治疗药物缺乏更广泛的基于证据的指南.
结论:
- 进一步严格的研究是必要的,以克服目前对LUTS的植物疗法研究的局限性.
- 需要对植物提取物进行标准化,改善监管框架.
- 解决这些问题将有助于将有效的植物性治疗方法纳入常规LUTS管理中.
相关概念视频
Drugs for Treatment of Constipation-Predominant IBS
109
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
109
Drugs for Treatment of Diarrhea-Predominant IBS
117
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
117
Irritable Bowel Syndrome III: Medical and Nursing Management
117
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
117
Cholinergic Antagonists: Therapeutic Uses
667
Antimuscarinic drugs have various therapeutic applications by inhibiting parasympathetic stimulation in different systems. Here are the key therapeutic uses of antimuscarinics:
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
667
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
99
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
99
Direct-Acting Cholinergic Agonists: Therapeutic Uses
615
Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
615


