营养状况和心力衰竭之间的关联与改善的喷射分数
Guanzhong Chen1, Chengchen Zhao1, Yu Jin2
1Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, China; State Key Laboratory of Transvascular Implantation Devices, Hangzhou, Zhejiang, 310009, China.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|April 22, 2025
概括
营养不良与心力衰竭患者的弹射率改善有关. 评估营养状况可能有助于预测心力衰竭的改善,减少排气分数 (HFrEF).
科学领域:
- 心脏病学 心脏病学
- 营养科学 营养科学
- 内部医学 内部医学
背景情况:
- 一部分心力衰竭患者的减少喷射分数 (HFrEF) 可以实现改善喷射分数 (HFimpEF).
- 营养不良在心力衰竭中普遍存在,并与更糟糕的结果有关.
- 营养状况和HFimpEF之间的关系尚不清楚.
研究的目的:
- 研究营养状况与住院HFrEF患者中HFimpEF的发展之间的关联.
- 为了确定营养指数是否可以预测HFimpEF.
主要方法:
- 对1057名住院的HFrEF患者进行了回顾性分析.
- 被归类为HFimpEF的患者 (随访EF>40%和≥10%绝对增加) 或持久的HFrEF.
- 用预后营养指数 (PNI),老年营养风险指数 (GNRI) 和控制营养状况指数 (CONUT) 评估营养状况. 用于分析的物流回归和受限制的立方线.
主要成果:
- 418名患者 (39.55%) 发生了HFimpEF.
- 在多变量调整后,增加的PNI,GNRI和CONUT得分与HFimpEF显著相关.
- 额外的CONUT得分显著改善了HFimpEF的预测模型 (AUC=0.698).
结论:
- 营养不良与患HFimpEF的可能性较低有关.
- 营养状况评估,特别是使用CONUT评分,在HFrEF患者中为HFimpEF提供增量预测价值.
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