COVID-19的嗅觉和味觉恢复时间评估:系统性审查和元分析
Mohadeseh Poudineh1, Amirhesam Amirbeik, Mohammad Dehghani Firouzabadi
1School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.. mo.poudineh@gmail.com.
Acta medica Indonesiana
|April 22, 2025
概括
大多数COVID-19患者在两周内恢复了嗅觉和味觉. 这项研究发现,这些常见症状的全球康复率很高,为患者提供了保证,并指导医疗保健专业人员进行诊断.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 嗅觉功能障碍 (嗅觉丧失) 和味觉功能障碍 (味觉丧失) 是与2019年新冠病毒病 (COVID-19) 相关的普遍症状.
- 了解这些感官障碍的恢复模式对于患者管理和流行病学评估至关重要.
研究的目的:
- 在被诊断为COVID-19的患者中系统评估嗅觉和味觉功能障碍的恢复率和持续时间.
- 通过元分析来综合现有数据,以提供聚合的恢复估计.
主要方法:
- 进行了系统性审查和随机效应元分析.
- 在PubMed和谷歌学者 (2020年4月至2022年10月) 进行了搜索,使用了COVID-19和嗅觉/味觉损失的综合关键词.
- 手动选参考资料并纳入125项研究,其中包括来自31个国家的COVID-19病例.
主要成果:
- 来自13,700名患者的数据显示,味觉丧失的恢复率为74%,平均恢复时间为11.44天.
- 来自20027名患者的数据显示,嗅觉丧失的恢复率为72%,平均恢复时间为12.87天.
- 恢复时间各不相同,大约为2至43天的味道和2至31天的气味.
结论:
- 在COVID-19患者中,嗅觉和味觉丧失的全球康复率很高,大多数患者在两周内康复.
- 嗅觉和味觉功能障碍是COVID-19诊断的重要指标.
- 医疗保健提供者应向患者保证,这些症状的预后普遍有利,并迅速恢复.
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