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微生物发酵对茶叶缓解肥胖症状的影响:从微生物组和代谢组学的见解

Liyuan Peng¹, Hongzhe Zeng¹, Liwei Wan¹

¹Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China; National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients Changsha 410128, China; Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Changsha 410128, China; Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops, Ministry of Agriculture and Rural Affairs of China, Hunan Agricultural University, Changsha 410128, China; Yuelushan Laboratory, Changsha 410128, China; National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Changsha 410128, China.

Food research international (Ottawa, Ont.)

|April 23, 2025

概括

微生物发酵不会显著改变深茶的抗肥胖功效. 发酵和非发酵茶都促进肠道细菌阿克尔曼西亚和短链脂肪酸的产生,有效地控制体重和代谢健康.

科学领域:

* 营养科学营养科学
* 微生物学微生物学
* 药理学药理学药理学

背景情况:

* 饮用深茶与抗肥胖作用有关,可能是通过促进阿克尔曼西亚的生长.
*微生物发酵对黑茶的关键加工步骤对其抗肥胖性能的影响尚不清楚.
* 由于原材料的变化,关于特定茶叶化合物与治疗结果之间的关系的研究有限.

研究的目的:

* 为了比较非微生物发酵茶 (NFT) 和微生物发酵茶 (FT) 的抗肥胖作用.
* 调查微生物发酵对茶叶减轻肥胖症状的能力的影响.
* 探索潜在的机制,包括对阿克克曼西亚和短链脂肪酸的影响.

主要方法:

*使用受控原材料对NFT和FT之间抗肥胖作用的比较分析.
*评估减轻超重,调节葡萄脂代谢和肝功能障碍.
*分析茶叶的化学成分,重点关注多和它们与阿克克曼西亚生长的关联.

主要成果:

* NFT和FT都在减少超重,改善葡萄脂代谢和缓解肝功能障碍方面表现出类似的有效性.
* 对两种茶类观察到可比的阿克尔曼西亚繁殖促进和增强的短链脂肪酸生产.
*微生物发酵改变了多烯的形状,但没有显著影响总体多烯含量,这对Akkermansia生长至关重要.

结论:

* 微生物发酵不会减少黑茶的抗肥胖功效.
* 对肠道微生物群 (Akkermansia) 和代谢物 (SCFA) 的类似作用解释了发酵和非发酵茶的可比效果.
*这项研究提供了关于茶叶加工,生物活性和肥胖管理之间的相互作用的见解.

关键词:

在阿克克曼斯的阿克克曼西亚.生物活性成分生物活性成分肠道代谢物的代谢物.我们的肠道微生物群.微生物发酵茶的茶.肥胖问题肥胖问题

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