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Updated: May 10, 2025

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
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Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Published on: November 8, 2015

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泰利塔西塞普和塔克罗利斯在治疗耐火性初级膜性脏病的协同作用:病例见解

Renwei Huang1, Yuhe Yin1, Zewen Zhao1

  • 1Department of Nephrology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China.

The American journal of case reports
|April 23, 2025
PubMed
概括

抵抗标准治疗的耐火性原发性膜性病 (pMN) 可以通过特利塔西和塔克罗利斯有效管理. 这种组合疗法显著降低了pMN患者的蛋白尿和脂酶A2受体 (PLA2R) 抗体.

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Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
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