在Sinopharm疫苗接种后出现意想不到的高氨酸性:一个病例报告
Behnam Dalfardi1, Niloofar Khoshnam Rad2, Tayebe Mohammad Alizade1
1Thoracic Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
BMC infectious diseases
|April 23, 2025
概括
接种COVID-19疫苗很少会导致过敏氨基酸,这种情况是具有高氨基酸细胞数量的情况. 这份案例报告强调了进一步研究疫苗相关血液学疾病的必要性.
科学领域:
- 血液学 血液学 血液学
- 疫苗学 疫苗学 疫苗学
- 免疫学 免疫学 免疫学
背景情况:
- 针对COVID-19的疫苗对于疫情控制至关重要.
- 虽然通常是安全的,但罕见的不良事件如过敏反应和血栓塞栓事件已被记录.
- 疫苗接种后很少报告血液学障碍,包括过高氨酸,其机制尚不清楚.
研究的目的:
- 报告COVID-19疫苗接种后出现过高氨酸的病例.
- 调查与非活化疫苗相关的潜在血液学不良事件.
主要方法:
- 一个66岁的男性的案例介绍.
- 记录了4063个细胞/μL的绝对乙氨基酸计数和淋巴腺病.
- 进行了广泛的调查,以排除其他原因.
主要成果:
- 患者在接种了BBIBP-CorV (Sinopharm) 疫苗的第三剂后两个月就出现过高氨酸和淋巴腺病.
- 没有发现观察到的发现的其他原因.
结论:
- 这一案例表明了COVID-19疫苗接种和高氨酸之间存在潜在的联系.
- 时间关联需要进一步调查与疫苗相关的血液学不良事件.
- 强调需要继续对罕见疫苗副作用进行监测和研究.
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