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评估中国原生猪品种肠道微生物群与生长特征之间的关系
Mengqing Zhou1, Lin Wu1, Xiao Sun1
1National Key Laboratory of Pig Genetic Improvement and Germplasm Innovation, Jiangxi Agricultural University, Nanchang, 330045, Jiangxi Province, China.
BMC veterinary research
|April 23, 2025
概括
肠道细菌会影响猪的生长. 像Prevotella这样的特定细菌群体对生长有负面影响,而像Rikenellaceae这样的细菌群体则对生长有积极影响,为猪的发育提供了洞察力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 肠道微生物群对于宿主新陈代谢和健康至关重要.
- 存在微生物与猪生长的关联,但缺乏特定的细菌识别和机制理解.
研究的目的:
- 研究中国原生猪品种的肠道微生物组成和生长特征之间的关系.
- 确定特定的细菌种群和与猪生长性能变化相关的功能途径.
主要方法:
- 16S rRNA基因测序500个来自Bamaxiang (BMX) 和Erhualian (EHL) 猪的肠道微生物样本.
- 使用两部分模型进行关联分析,将细菌组成与生长特征联系起来.
- 预测肠道微生物组的功能能力分析.
主要成果:
- 固菌与细菌的比率与BMX猪的平均每日增长有负相关性.
- 来自Prevotella和Oscillospiraceae的特定扩展序列变异 (ASV) 与生长有负相关性,而Muribaculaceae和Rikenellaceae的ASV显示出正相关性.
- 与消化,新陈代谢和异生菌相关的功能途径与生长有积极的关联,而排泄系统途径与生长有负相关.
结论:
- 肠道微生物群的组成显著影响猪生长性能.
- 鉴定的细菌种群和功能途径为进一步研究微生物对猪生长的影响背后的机制提供了基础.
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