类风湿性关节炎患者的虚弱和口腔功能之间的关联:一个多中心的观察性研究
Yasumori Sobue1, Mochihito Suzuki2, Yoshifumi Ohashi3
1Department of Orthopedic Surgery, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Achi, Japan.
Archives of rheumatology
|April 23, 2025
概括
虚弱与风湿性关节炎 (RA) 患者口腔功能下降有关. 监测口腔健康可以帮助早期发现脆弱性,并指导干预以改善患者福祉.
科学领域:
- 类风湿病学 类风湿病学
- 老年学是一门学科.
- 口腔健康 口腔健康
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性炎症性疾病,影响关节.
- 虚弱是一种对压力因素的脆弱性增加的状态,在老年人中很常见.
- 口腔功能下降可能会影响RA患者的营养和生活质量.
研究的目的:
- 调查RA患者的虚弱和口腔功能之间的关联.
- 确定用于RA早期脆弱性检测的实用标记.
- 探索潜在的干预策略来治疗RA的脆弱性.
主要方法:
- 一项661名RA患者的多中心观察队列研究 (T-FLAG).
- 使用Kihon检查清单 (KCL) 评估的脆弱性 (得分≥8).
- 通过KCL问题评估口腔功能,评估饮食困难,窒息和口腔干燥;使用ROC曲线和后勤回归.
主要成果:
- 39.5%的RA患者是脆弱的,较高的脆弱率与较差的口腔功能相关.
- 2分的口腔功能得分最好地识别了脆弱性 (89.2%的特异性,54.8%的灵敏度).
- 年龄和健康评估问卷-残疾指数 (HAQ-DI) 是口腔功能下降的重要因素.
结论:
- 虚弱与RA患者的口腔功能下降密切相关.
- 在RA患者的口腔功能监测可以作为虚弱的潜在标志物.
- 针对口腔功能的干预措施可以减少虚弱的风险,并改善RA患者的福祉.
相关概念视频
Assessment of the Mouth
99
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
99
Bone Disorders
3.3K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.3K
The Effect of Aging on Tissues
2.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.0K


