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超尿血和中风发病率和死亡率的风险:系统性审查和元分析

Haiyan Jiang^1,2, Yunyi Su¹, Ruixue Liu¹

¹School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, China.

Archives of rheumatology

|April 23, 2025

概括

高尿酸水平 (超尿血) 显著增加中风发病率和死亡率的风险. 这种关联在女性和缺血性中风中更为明显.

科学领域:

神经学神经学
心脏病学心脏病学
代谢障碍代谢障碍代谢障碍

背景情况:

关于高尿血和中风风险之间的联系仍在争论中.
尿酸过高是一种代谢状况,其特征是尿酸水平升高.

研究的目的:

系统地审查和元分析高尿血和中风发病率和死亡率之间的关联.
为了澄清高尿酸和中风风险之间的有争议的关系.

主要方法:

我们对PubMed,Embase,Web of Science和Cochrane图书馆进行了全面的搜索.
包括前性研究,对高尿血和中风风险进行多变量调整的估计.
用相对风险 (RRs) 和95%的置信区间 (CI) 进行了元分析.

主要成果:

分析了22项涉及770,532名成年人的研究.
高尿路血症显著增加了中风发病率 (RR, 1.42) 和死亡率 (RR, 1.53).
女性的风险在发病率和死亡率以及缺血性中风死亡率方面都较高.

结论:

这项研究证实了高尿血和中风风险增加之间存在显著的关联.
由于高尿血的中风发病率和死亡率的风险在女性中更为明显.
高尿路血是中风的潜在危险因素,特别是缺血性中风.

关键词:

群组研究是一项群组研究.超血症是什么意思这是一个元分析.一次中风. 一次中风.

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