生育间隔与绝经后妇女抑郁症患病率的关联
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Ronghua Zuo1, Yan Chen2, Qiaoying Zhu3
1Department of Anesthesiology, Peking University Third Hospital, No. 49, North Garden Street, Haidian District, Beijing 100191, China.
Depression and anxiety
|April 23, 2025
概括
短的分娩间隔和极端的分娩年龄与美国绝经后妇女的更高的抑郁率有关. 早期和晚期生育,以及短暂的间隔,可能会增加心理健康风险.
科学领域:
- 生殖健康 生殖健康
- 精神卫生流行病学 精神卫生流行病学
- 社会人口统计学 社会人口统计学
背景情况:
- 绝经后抑郁症是一个重大的公共卫生问题.
- 了解与生殖史相关的风险因素对于有针对性的干预至关重要.
- 之前的研究还没有完全阐明分娩时间和间隔对这一特定人口群体抑郁症的影响.
研究的目的:
- 为了研究分娩间隔和美国绝经后妇女中抑郁症的患病率之间的联系,她们确实有两个孩子.
- 检查第一个出生年龄 (AFB),最后一个出生年龄 (ALB) 和出生间隔与抑郁风险之间的关系.
主要方法:
- 利用了2005-2018年国家健康和营养检查调查 (NHANES) 的数据.
- 采用加权多变量后勤回归,限制立方线 (RCS) 和子组分析.
- 包括2375名绝经后妇女,分娩两次,分析基于分娩时间和间隔的抑郁症患病率.
主要成果:
- 共有271名 (11.4%) 参与者报告患有抑郁症.
- RCS模型显示了第一个出生年龄 (AFB) 和最后一个出生年龄 (ALB) 与抑郁症患病率之间的U形关联.
- 在分娩间隔和抑郁风险之间观察到大约L形的相关性,这表明较短的间隔与更高的风险有关.
结论:
- 早产和晚产都与绝经后妇女抑郁症风险增加有关.
- 在这个人群中,出生间隔短是患抑郁症的重要风险因素.
- 调查结果强调,需要针对性地进行心理健康查,并为具有特定生育模式的妇女提供支持.
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