在患有严重大动脉狭窄症的患者中,以正常的射出分数评估组织年均运动位移
Jie Feng1, Yao Li2, Shiyuan Zhang1
1Department of Cardiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Journal of clinical ultrasound : JCU
|April 23, 2025
概括
组织环状运动位移 (TMAD) 参数可以在严重的大动脉狭窄患者中早期检测左心室缩功能障碍,其中有保存的射出分数. TMADmid-A4C是主要心血管不良事件的强有力的预测因素.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏机械学 心脏机械学
背景情况:
- 严重的大动脉狭窄症 (AS) 经常呈现出保存的喷射分数,掩盖了潜在的左心室缩功能障碍.
- 早期检测系统功能障碍对于AS患者的风险分层和管理至关重要.
研究的目的:
- 评估组织环状运动移位 (TMAD) 在评估严重AS的左心室缩功能时的实用性.
- 在严重AS患者中识别主要不良心血管事件 (MACE) 的风险因素,这些患者具有保存的射出分数 (LVEF ≥50%).
主要方法:
- 追溯分析81名严重AS患者和22名对照组.
- 纵向随访以追踪MACE发生率.
- 卡普兰-梅尔生存分析,以评估TMAD参数的预后意义.
主要成果:
- TMAD参数与左心室全球纵向应变 (LVGLS) 有负相关性.
- 过导管大动脉置换 (TAVR) 改善了心肌纵向缩功能.
- 14.8%的AS患者在随访期间经历了MACE.
结论:
- TMAD参数能够在严重的AS中早期检测到左心室缩功能障碍,并具有正常的射出分数.
- TMAD与LVGLS有很好的相关性.
- TMADmid-A4C是MACE的显著预测因子,在重症AS患者中具有保存的LVEF.
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