免疫疾病:分级和实验室诊断的当前方法
Anna A Starshinova1,2,3, Andrey An Savchenko4, Alexander Borisov4
1Department of Mathematics Computer Science, St. Petersburg State University, 199034 St. Petersburg, Russia.
概括
了解免疫系统疾病及其实验室诊断对于管理各种疾病至关重要. 识别免疫细胞和分子参与方面的进展为改善诊断和向治疗提供了有希望的途径.
科学领域:
- 免疫学 免疫学 免疫学
- 临床诊断 临床诊断 临床诊断
- 病变的发生和发病.
背景情况:
- 了解免疫反应异常对于管理传染病和瘤疾病至关重要.
- 免疫疾病的实验室诊断有助于患者管理.
- 目前对免疫媒介疾病病原发生的知识仍然不完整.
研究的目的:
- 系统地审查有关免疫疾病的当前文献.
- 用实验室技术分析免疫疾病的诊断可能性.
- 探索临床表现和免疫系统功能障碍之间的联系.
主要方法:
- 在过去十年中对国际数据库进行系统的文献分析.
- 通过免疫细胞和可溶性分子诊断免疫病理过程的数据的审查.
- 对自身免疫过程的抗体确定性的检查.
主要成果:
- 血液学,流细胞计和ELISA等实验室技术用于收集有关免疫系统功能障碍的数据.
- 尽管进行了广泛的研究,但大多数免疫媒介疾病的发病因子尚未完全理解.
- 在基于T辅助细胞种群和细胞因子参与的基础上对免疫介导疾病进行分类方面取得了进展.
结论:
- 对免疫细胞和分子参与的持续研究对诊断和治疗有希望.
- 根据炎症反应对免疫介导疾病的分类代表了显著的进步.
- 对T辅助细胞和细胞因子的进一步研究可能会导致新的诊断和治疗点.
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