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Updated: May 10, 2026

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基托桑纳米颗粒悬浮剂可以在体外侵蚀性挑战后最大限度地减少质损失

Renata Cristina Sobreira França1, Rebeca Tibau Aguiar Dias1, Ranam Moreira Reis2

  • 1Universidade Federal da Paraíba (UFPB), Programa de Pós-Graduação em Odontologia, João Pessoa, Paraíba, Brasil.

Journal of applied oral science : revista FOB
|April 23, 2025
PubMed
概括

素纳米颗粒 (ChNPs) 有效地减少了由于酸性侵蚀而导致的面膜损失. 这项研究表明,ChNP是一种有前途的新材料,可以防止牙面膜侵蚀.

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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are employed to...