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Updated: May 10, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

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利用基因型和表型数据进行人口规模变异分类,使用大型语言模型和贝叶斯推理

Toby R Manders1, Christopher A Tan2, Yuya Kobayashi2

  • 1Labcorp Genetics Inc, 1400 16th Street, San Francisco, CA, 94103, USA. toby.manders@labcorp.com.

Human genetics
|April 23, 2025
PubMed
概括

一种新的机器学习方法有效地利用患者数据来改善遗传变异分类,在遗传性疾病测试中显著减少不确定的意义 (VUS) 的变异,并帮助临床决策.

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