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Updated: Apr 6, 2026

Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability
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生物材料的冷保存:应用和经济前景

Suja Aarattuthodi1, David Kang2, Sanjay Kumar Gupta3

  • 1Plant Genetics Research Unit, United States Department of Agriculture - Agricultural Research Service, Columbia, MO, 65211, USA. Suja.Aarattuthodi@usda.gov.

In vitro cellular & developmental biology. Animal
|April 23, 2025
PubMed
概括

冷保存使生物材料在低温下长期储存,从而最大限度地减少细胞损伤. 目前正在进行的研究旨在改进技术,使这种至关重要的技术在医学,农业和保护方面更容易获得.

关键词:
这是生物银行.结冷保存是一种冷保存.冰冷保护剂 冰冷保护剂冰冷治疗药物 冰冷治疗药物功能性的功能性.可行性 可行性.玻璃化是一种玻璃化过程.

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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