相关实验视频
Updated: May 10, 2025
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
14.2K
乳杆菌属复杂益生菌诱导的变化对马类阴茎微生物群
Fiona Herzog1, Kassandra R Crissman1, Kalie F Beckers1
1Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Veterinary sciences
|April 23, 2025
概括
局部益生菌改变了马的阴茎微生物群,观察到细菌群体的显著变化. 这种干预导致马匹怀孕率达到85%,这表明马匹繁殖可能有好处.
科学领域:
- 马类生殖微生物学 马类生殖微生物学
- 微生物组的分析
- 益生菌在动物健康中的应用.
背景情况:
- 马下生殖道 (LRT) 失生症与子宫内膜炎和胎盘炎有关.
- 甲基因组分析检测到无法培养的细菌,为微生物群提供了更深入的见解.
- 阴蒂微生物群在马匹生殖健康中的作用需要进一步研究.
研究的目的:
- 为了确定雌性母阴蒂是否含有独特的微生物群.
- 评估含有益生菌的乳杆菌属复合体 (LGC) 对马类阴茎微生物群的影响.
- 为了评估阴蒂LGC应用是否影响早期怀孕率与行业标准相比.
主要方法:
- 在每天局部LGC应用之前和之后,从12只雌雄的雌雄中收集了无菌的阴蒂拭子.
- 在Illumina Miseq平台上的16SrRNA测序被用来分析细菌DNA.
- 细菌的丰富性和多样性得到了统计评估,显著性设置为p < 0.05.
主要成果:
- 应用LGC改变了细菌种群,减少了Desulfobacterota,增加了Corynebacterium spp.
- 亚克蒂诺细菌和富索细菌 spp. 显示时间依赖的增长,而Mobiluncus spp. 克里斯森和克里斯森鱼_R-7_组减少.
- LGC显著改变了阴茎微生物群的β多样性,但没有改变阴茎微生物群的α多样性.
结论:
- 马的阴茎微生物组合被局部LGC应用改变了.
- 该研究在用LGC治疗的母马中实现了85%的怀孕率,符合行业标准.
- 需要进一步的研究来阐明LRT微生物组和益生菌在马匹繁殖成功中的作用.
相关概念视频
01:29Bacterial Flora of the Large Intestine
359
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
359
01:18Surface Membrane Barriers
668
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
668