住宅绿色与下甲状腺结节的患病率有关:中国的一项全国性研究
Siying Liu1, Cihang Lu2, Yongze Li1
1Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China.
概括
生活在更绿色的地区与较少的甲状腺结节有关. 这项研究发现,通过NDVI和EVI测量较高的住宅绿色与较低的甲状腺结节患病率有关.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 内分泌学 在内分泌学.
背景情况:
- 在全球范围内,甲状腺结节的患病率正在上升.
- 环境因素越来越多地被认为是甲状腺疾病的潜在贡献者.
- 住宅绿色是生活环境的一个可衡量的方面.
研究的目的:
- 调查住宅绿色和甲状腺结节的流行之间的联系.
- 利用来自中国的大规模流行病学数据探索这种关系.
主要方法:
- 对73,728名参与者进行了一项全国性横截面调查.
- 住宅绿地使用规范差异植被指数 (NDVI) 和增强植被指数 (EVI) 来量化.
- 通过超声波诊断甲状腺结节 (>10毫米);使用逻辑回归和受限立方脊柱分析.
主要成果:
- 在住宅绿色和甲状腺结节患病率之间发现了显著的反向关联.
- 较高的NDVI和EVI四分位数与较低的甲状腺结核患病率有关 (例如,NDVI500 Q4 OR=0.53).
- 敏感性分析,包括替代结节定义和子组分析,证实了研究结果的可靠性.
结论:
- 住宅绿化增加与甲状腺结节的发病率降低有关.
- 这项研究提供了新的证据,将环境绿色与甲状腺健康联系起来.
- 需要进一步的研究来阐明这种关联背后的机制.
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