痴呆症对2型糖尿病患者视觉相关功能表现的影响
Li-Ting Tsai1, Chung-Sen Chen2, Chia-Wei Hung3
1Li-Ting Tsai, PhD, is Assistant Professor and Occupational Therapist, School of Occupational Therapy, National Taiwan University, Taipei City, Taiwan, and Department of Ophthalmology, National Taiwan University Hospital, Taipei City, Taiwan.
概括
2型糖尿病 (T2DM) 的并发症可能会增加痴呆症的风险. 患有T2DM和痴呆症的患者在功能视力方面经历了显著的下降,影响了日常活动和生活质量.
科学领域:
- 眼科和神经病学 眼科和神经病学
- 老年医学 老年医学
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 是导致视力丧失的主要原因.
- 痴呆症越来越被认为是一个重大的公共卫生问题.
- T2DM并发症,视力障碍和认知能力下降之间的相互作用尚未完全理解.
研究的目的:
- 调查T2DM患者与糖尿病相关的眼睛疾病和痴呆症之间的关联.
- 评估痴呆症对T2DM患者视觉相关生活质量 (VRQoL) 和日常生活活动 (ADL) 的影响.
- 探索糖尿病视网膜病变严重程度和视力敏度 (VA) 之间的关系.
主要方法:
- 追溯队列和嵌套病例控制研究设计.
- 将4454名T2DM患者纳入第1子研究.
- 在子研究2中,对33名患有痴呆症的T2DM患者与67名匹配的对照进行了比较.
- 评估使用国家眼科研究所视觉功能问卷 (NEI-VFQ 25) 和功能视觉表现的修订自报评估 (R-SRAFVP).
主要成果:
- 在增殖性糖尿病视网膜病变和痴呆症之间发现了边缘显著的关联.
- 患有T2DM和痴呆症的患者在多个R-SRAFVP和NEI-VFQ 25子尺度中显示出功能视力的显著下降.
- 两组之间没有观察到视敏度 (VA) 的显著差异.
结论:
- 痴呆症对T2DM患者的功能视觉和与视觉相关的生活质量产生重大影响.
- 这些发现突出了T2DM,痴呆和视力之间的复杂的相互关系.
- 职业治疗师应优先考虑T2DM痴呆患者的功能视觉评估,以指导干预.
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