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对大脑体积的多发性硬化症特定参考曲线,以解释疾病严重程度.

David Rudolf van Nederpelt1, Lonneke Bos1, Rozemarijn M Mattiesing1

  • 1MS Center Amsterdam, Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, the Netherlands.

Neurology
|April 23, 2025
PubMed
概括

一个新的多发性硬化症 (MS) 特定的大脑体积模型改善了与健康对照 (HC) 参考曲线相比的疾病严重程度评估. 这种多发性硬化模型与疾病严重程度得分更好地相关,有助于MS患者的临床实施.

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Multiple Sclerosis l: Introduction01:19

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...