更高的预后营养指数与较低的肉类的发病率有关
Lulu Cheng1, Sheng Hu2, Qinggang Wu3
1College of Acupuncture-Moxibustion and Tuina, Anhui University of Chinese Medicine Hefei 230012, China; Graduate School, Wuhan Sports University Wuhan 430079, China.
概括
更高的预后营养指数 (PNI) 与降低肌肉衰退的疾病 - - 肉症的风险有关. 这项研究发现,在成年人中,PNI和肉症发病率之间存在显著的负相关性.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 标志着肌肉质量和功能逐渐丧失的萨尔科佩尼亚,受到营养状况的显著影响.
- 了解营养标志物和肉症之间的关系对于开发有效干预措施至关重要.
- 预后营养指数 (PNI) 是与肌肉健康相关的营养状况和免疫功能的潜在指标.
研究的目的:
- 在大量成年人群中调查预后营养指数 (PNI) 与肉症之间的关联.
- 为了确定PNI水平是否能预测患上萨科佩尼亚的风险.
- 使用可靠的统计方法和子组分析来探索这种关系.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) 的数据,其中包括8058名成年参与者.
- 采用多重线性回归分析来评估PNI和肉症之间的关联.
- 应用了通用添加模型和平滑曲线拟合,以进一步阐明剂量-反应关系.
主要成果:
- 在PNI水平和肉症之间观察到显著的负相关性 [回归系数0.89 (0.85,0.93) ].
- 与最低四分位数相比,PNI最高四分位数的个体表现出缩症风险降低了52% [赔率比0.48 (0.31,0.74) ].
- 这种PNI和肉症风险之间的反向关系在各种子组中是一致的.
结论:
- 更高的预后营养指数 (PNI) 独立地与较低的麻症风险有关.
- 在临床实践中,PNI可以作为一个有价值的营养生物标志物来评估肉症风险.
- 保持最佳的营养状况,如PNI所示,对于保持成年人的肌肉健康和功能很重要.
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