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Updated: May 10, 2025

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BATF2-ATF3轴通过诱导线粒体功能障碍加剧椎间盘退化

Cheng Yu1, Chun Liu1, Wenhao Kuang1

  • 1Department of Spinal Surgery, Orthopedic Medical Center, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.

International immunopharmacology
|April 23, 2025
PubMed
概括

这项研究揭示,基本氨酸拉链ATF类转录因子2 (BATF2) 通过增加细胞死亡和基质分解,促进椎间盘退化 (IVDD). 针对BATF2-ATF3途径可以治疗IVDD.

关键词:
在ATF3中使用ATF3.最常见的BATF2方法椎间盘退化 椎间盘退化线粒体功能障碍 线粒体功能障碍线粒体的氧化还原稳态同质化.

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