避开行为调解了对跌倒的担忧和多发性硬化症中运动能力受损之间的关系
Taylor N Takla1, Patrick G Monaghan2, Ana M Daugherty3
1Neuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit MI, USA; Translational Neuroscience Program, Wayne State University, Detroit MI, USA.
Multiple sclerosis and related disorders
|April 23, 2025
概括
担心患上多发性硬化症 (MS) 与移动性问题有关,避开行为起着关键作用. 对跌倒和运动障碍的担忧之间的这种联系对于MS的跌倒者和非跌倒者都是相似的.
科学领域:
- 神经学 神经学
- 康复科学 康复科学 康复科学
- 运动科学 运动科学
背景情况:
- 担心跌倒 (CAF) 是多发性硬化症 (MS) 的一个普遍问题.
- 风会对流动性和日常活动产生负面影响,不管有没有风史.
- 了解导致MS运动障碍的因素对于有效的干预至关重要.
研究的目的:
- 调查回避行为在调解CAF与MS运动障碍之间的关系中的作用.
- 为了确定这种调解效应是否在患有多发性硬化症的个人之间有所不同,他们已经跌倒了,而那些没有跌倒的人.
主要方法:
- 用结构方程建模来测试一个调解模型.
- 参与者填写了关于CAF,避开行为和行走的验证问卷.
- 进行了基于实验室的行走和平衡评估,以客观地衡量移动性.
主要成果:
- 避开行为占CAF对移动性的总影响的46.96%.
- 避免行为的调解作用在堕落者和非堕落者之间是统计学上一致的.
- 根据跌倒史,没有观察到中介效应的显著差异.
结论:
- 避开行为是与MS中CAF相关的运动障碍的重要调解者.
- 避开行为对流动性的影响在MS患者中是普遍和一致的,无论他们的跌倒状况如何.
- 针对避开行为可能是一个可行的策略,以改善患有CAF的MS个体的流动性.
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