一个综合寒冷暴露,呼吸练习和正念作为多发性硬化症神经心理方面的补充治疗的补充培训计划 - 一项试点干预研究
Darina Slezáková1, Louise Mária Adamová1, Peter Marček1
1Second Department of Neurology, Faculty of Medicine, Comenius University in Bratislava, Slovakia.
Multiple sclerosis and related disorders
|April 23, 2025
概括
威姆·霍夫方法 (WHM) 显著改善了多发性硬化症 (MS) 患者的认知功能,疲劳,焦虑和抑郁. 这种非药理学方法为MS相关的神经心理症状提供了一个有前途的补充治疗方法.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 免疫学 免疫学 免疫学
背景情况:
- 多发性硬化症 (MS) 经常导致认知障碍,疲劳和情绪障碍.
- 这些神经精神症状往往会抵抗常规的疾病修饰和症状治疗.
- 对于管理多发性硬化患者的福祉,越来越多地采用整体方法.
研究的目的:
- 评估Wim Hof方法 (WHM) 作为MS患者神经精神病症状的补充治疗的疗效.
- 评估12周WHM计划对认知,疲劳,焦虑和抑郁症的影响.
主要方法:
- 采用了一种随机干预研究设计.
- 参与者被分配到一个为期12周的WHM培训计划或一个没有干预的对照组.
- 在干预期之前和之后,使用经过验证的天平和问卷测量神经精神病症状变化.
主要成果:
- 与对照组 (n=13) 相比,WHM组 (n=12) 显示出显著的改善.
- 关键的改善包括增强的认知 (SDMT,TMT-A,TMT-B),减少疲劳 (FSMCC),以及减少焦虑 (GAD) 和抑郁 (PHQ-9) 评分.
- 对所有测量结果 (p < 0.05) 观察到统计学意义.
结论:
- 威姆·霍夫方法显示出作为MS有效的非药物补充疗法的潜力.
- 在患有多发性硬化症的个体中,WHM可能是管理衰弱性神经精神病症状的可行选择.
- 需要进一步的研究来探索WHM在MS的长期影响和潜在机制.
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