CD47

Yajuan Su1, Jingyu Sun2, Xiaobo Li3

  • 1Institute for Regenerative Medicine, State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Sports and Health Research Center, Tongji University Department of Physical Education, Tongji University, Shanghai 200092, China; Tsingtao Advanced Research Institute, Tongji University, Qingdao 266071, China.

Cell reports. Medicine
|April 23, 2025
PubMed
概括

阻断CD47的抗体治疗可以对抗肥胖和代谢功能障碍. 这种治疗激活了骨肌中的AMPK通路,改善了葡萄糖耐受性和运动能力.