相关实验视频
Updated: May 10, 2025

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A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
Published on: April 30, 2020
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对结核病新型治疗方案的TB-PRACTECAL临床试验的成本分析
Dzintars Gotham1, Manuel Martin1, Melissa J Barber1,2
1MSF Access Campaign, Geneva, Switzerland.
PLOS global public health
|April 23, 2025
概括
这项研究详细介绍了针对耐药结核病的TB-PRACTECAL临床试验的3390万欧元成本. 它强调了72%的成本是基于现场的,员工是最大的支出,在试验支出中提供了透明度.
科学领域:
- 卫生经济学 卫生经济学
- 临床试验管理 临床试验管理
- 传染病研究 传染病研究
背景情况:
- 临床试验占制药开发费用的很大一部分.
- 关于个人临床试验成本的公开报告是罕见的.
- 结核-PRACTECAL试验的目的是为抗药结核病寻找一种新的治疗方法.
研究的目的:
- 在低资源环境中分析关键临床试验的支出.
- 为了证明报告详细的临床试验成本的可行性.
- 为特定试验提供透明的成本分析.
主要方法:
- 对无国界医生组织 (MSF) 结核病实用试验的会计文件进行分析.
- 按类别,年份和试验地点划分成本.
- 与临床试验成本估计的现有文献进行比较.
主要成果:
- 结核病PRACTECAL试验总成本为3390万欧元,平均每名患者为61460欧元.
- 现场活动占总成本的72%,其中人力是最大的组成部分 (43%).
- 各站点的成本变化与先前存在的基础设施水平有关.
结论:
- 这是对特定临床试验的直接支出进行的首次全面分析,并提供详细的细分.
- 药物开发成本的透明度对于公平的生物医学研发和药物定价至关重要.
- 该研究表明,在临床研究中详细报告成本的可行性.
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