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来自印度的第一个人类帕雷科病毒中枢神经系统感染:两例病例的报告

Kakhangchung Panmei¹, Deepayan Biswas¹, Shoba Mammen¹

¹Department of Clinical Virology, Christian Medical College, Vellore, India.

Indian journal of medical microbiology

|April 23, 2025

概括

人类帕雷科病毒 (HPeV) 可以在儿童和成人中引起严重的中枢神经系统 (CNS) 感染. 这项研究报告了印度首次出现HPeV脑膜炎和脑膜炎的病例.

科学领域:

神经学神经学
传染性疾病传染性疾病
病毒学病毒学

背景情况:

人类帕雷科病毒 (HPeV) 感染通常表现温和,但可能导致严重的神经疾病,如脑膜炎和脑炎.
虽然HPeV在儿童中很常见,但严重的中枢神经系统感染在成年人中越来越多.

研究的目的:

报告在印度诊断的急性HPeV中枢神经系统 (CNS) 感染的初始病例.
在成人和儿科患者中描述这些HPeV中枢神经系统感染的临床表现和结果.
要突出HPEV作为不同人群中显著的神经病原体的日益扩大的临床认可.

主要方法:

病例系列描述了已确认HPeV中枢神经系统感染的患者的临床数据.
通过分子方法 (如PCR) 在脑脊液 (CSF) 样本上进行诊断确认.
临床和流行病学数据的收集和分析.

主要成果:

介绍了来自印度的成年人患急性HPeV脑膜炎和儿童患者患脑膜炎的首例记录.
证实HPeV是中枢神经系统感染的致病原体,超出了典型的儿科人口统计.
报告病例的详细临床和实验室发现.

结论:

在印度的儿童和成人中,在中枢神经系统感染 (包括脑膜炎和脑炎) 的差异诊断中应考虑HPeV.
这些发现强调了需要提高对该地区HPeV感染的认识和诊断能力.
需要进一步的研究来了解印度和类似环境中HPeV的流行病学和临床影响.

关键词:

中枢神经系统感染.人类帕雷科病毒 (HPeV)这是一个PCRPCR.

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