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Naledi Adam¹, Ronald Mooiweer², Andrew Tyler¹

¹School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

|April 23, 2025

概括

一种新的3D运动校正技术,用于同时进行多切片平衡稳定状态自由前行 (SMS-bSSFP) 心肌 perfusion,显著减少左心室运动. 这种先进的技术可以提高自由呼吸心脏MRI的准确性和图像质量.

科学领域:

心血管成像 - 心血管成像
磁共振成像是一种磁共振成像技术.
医学物理医学物理

背景情况:

开发用于自由呼吸心肌输液的先进成像技术对于准确的诊断至关重要.
同时多切片 (SMS) 均衡稳定状态自由前置 (bSSFP) 提供了高空间分辨率和覆盖的潜力.
运动器件在心脏MRI中仍然是一个挑战,特别是在自由呼吸的过程中.

研究的目的:

开发和评估一种新的3D运动校正SMS-bSSFP获取方法,用于自由呼吸的心肌 perfusion.
评估快速腹膜呼吸导航器 (fastNAV) 与SMS-bSSFP一起用于未来切片跟踪的有效性.
将新的3D运动校正策略与标准的平面内校正方法进行比较.

主要方法:

在SMS-bSSFP序列中实现快速隔膜呼吸导航器 (fastNAV) (<15毫秒),用于潜在的切片跟踪.
使用直线图像注册纠正剩余的2D平面内运动.
开发的SMS-fastNAV方法与1.5T的10名患者的参考SMS perfusion协议 (SMS-Ref) 的比较,使用DICE系数 (avDICE) 和质量中心移位 (avCOM) 评估左心室 (LV) 运动.

主要成果:

与SMS-Ref在非刚性注册之前相比,SMS-fastNAV显示了明显较低的剩余LV运动,由更高的avDICE (0.93±0.02对比0.89±0.04) 和降低的avCOM (2.82±0.89mm对比4.23±1.29mm) 表示.
在非刚性注册之后,SMS-fastNAV保持了更高的avDICE (0.95±0.01对比0.94±0.02) 并显示了降低avCOM (0.97±0.21mm对比1.01±0.25mm) 的趋势,这表明改进了通过平面运动校正.
在SMS-fastNAV和SMS-Ref方法 (1.79±0.50与2.00±0.59) 之间没有观察到主观图像质量的统计学上显著差异.

结论:

成功开发了一种用于自由呼吸SMS-bSSFP perfusion的3D运动校正策略.
开发的策略提供了改进的运动校正与标准的飞机内图像记录单独相比.
这种技术可以实现高空间覆盖率和分辨率的自由呼吸心肌 perfusion MRI.

关键词:

这是一种自由呼吸.完整的左心室覆盖范围运动校正,运动校正.心肌 perfusion 影像成像 - - 心肌 perfusion 影像成像这是一个前性的前性.同时的多片切片.

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