心肌原生T1和5T的细胞外体积测量:可行性研究和初步经验
概括
这项研究表明,5特斯拉的T1映射对于评估心肌病是可行的. 5T时心肌T1的初步参考值在健康志愿者和患者中确定.
科学领域:
- 心血管磁共振成像 - 心血管磁共振成像
- 量化心肌评估 量化心肌评估
背景情况:
- T1映射是一种可重复的方法,用于对心肌病的定量评估.
- 调查5T心肌T1映射可行性和参考值至关重要.
研究的目的:
- 评估T1映射在5特斯拉 (5T) 的可行性,以进行心肌评估.
- 确定5T时心肌T1的初步参考值.
主要方法:
- 在28名健康志愿者和11名患者中,在5T进行了心血管磁共振成像.
- 采用经过运动校正的修改的Look-Locker反转恢复序列来获得T1映射.
- T1值被量化为每个细分,每个切片和全球.
主要成果:
- 健康的志愿者显示平均全球原生T1值为1506.2 ± 41.7 ms.
- 与健康志愿者相比,患者表现出较高的T1原生值 (1638.7 ± 108.6毫秒).
- 在本地T1测量中观察到出色的可重现性.
结论:
- 在5T的T1映射量化是可行的.
- 在5T处的平均原生T1值为这个特定的磁共振设置提供了参考值.
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