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Updated: May 10, 2025

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
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Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport

Published on: November 27, 2016

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通过对功能受损突变物进行NMR动态分析,确定人类胆汁胆汁酸结合蛋白的位点选择性的决定因素

Tamara Teski1, Gergő Horváth2, Orsolya Toke2

  • 1Centre for Structural Science, HUN-REN Research Centre for Natural Sciences, 2 Magyar tudósok körútja, Budapest H-1117, Hungary; Doctoral School of Biology, Institute of Biology, ELTE Eötvös Loránd University, Budapest 1117, Hungary.

Journal of structural biology
|April 23, 2025
PubMed
概括

人体胆汁胆汁酸结合蛋白 (hI-BABP) 的相互作用使用NMR进行了研究. Q51A突变破坏了hI-BABP的稳定,影响了胆汁盐的结合和蛋白质动态,对胆汁盐的贩运有影响.

关键词:
胆盐 胆盐 胆盐 胆盐肝脏内循环 肝脏内循环结合带的结合.核磁共振光谱法 (NMR) 是一种光谱法.蛋白质动力学 蛋白质动力学网站选择性的选择性

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