在艾滋病毒预防试验的参与者中,艾滋病毒风险感知,信任和PrEP坚持:一种定性纵向研究,南非
Rujeko Samanthia Chimukuche1,2, Londiwe Shandu3, Silindile Zulu3
1Africa Health Research Institute, Durban, KwaZulu-Natal, South Africa rujeko.chidawanyika@ahri.org.
BMJ open
|April 23, 2025
概括
参与者对暴露前预防 (PrEP) 疗效的信心,在临床试验参与的推动下,显著影响了他们对这种艾滋病毒预防方法的坚持. 一贯的健康倡议促进了风险意识和PrEP的普及.
科学领域:
- 公共卫生 公共卫生
- 临床研究 临床研究
- 行为科学 行为科学
背景情况:
- 对于有效的艾滋病毒预防和治疗,高度坚持是至关重要的.
- 信任显著影响个人对艾滋病毒风险的看法.
- 了解守驱动因素是优化艾滋病毒预防策略的关键.
研究的目的:
- 质量地探索临床试验参与者对艾滋病风险的看法.
- 了解个人如何评估和应对艾滋病毒风险.
- 检查口服暴露前预防 (PrEP) 的吸收和遵守情况.
主要方法:
- 从南非的一项艾滋病毒预防试验数据的定性分析.
- 针对30名参与者进行了有目的的抽样采访,采访时间分为三个时间点.
- 使用信任,信心和合作框架进行分析.
主要成果:
- 持续参与临床试验影响了继续使用PrEP.
- 参与者对PrEP在降低艾滋病毒感染率方面的有效性充满信心是关键因素.
- 对干预措施的信任与持续坚持PrEP相关.
结论:
- 清晰,一致的健康促进提高了对艾滋病毒风险的自我意识.
- 有效的健康倡议可以提高对艾滋病毒预防方法 (如PrEP) 的理解和采用.
- 建立信任对于促进遵守艾滋病毒预防战略至关重要.
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