生物标志物的使用在精确的健康症状科学机遇和挑战
Carolyn S Harris1, Yvette P Conley1, Jinbing Bai2
1School of Nursing, University of Pittsburgh, Pennsylvania.
Seminars in oncology nursing
|April 23, 2025
概括
精确的健康症状科学使用奥米克和各种决定因素来了解患者的症状. 生物标志物发现推动了个性化的管理策略,改善了各种疾病的生活质量.
科学领域:
- 精确的健康症状科学将以人为中心的方法与健康的因素和决定因素相结合.
- 专注于症状体验的个体间差异,以制定有针对性的管理策略.
背景情况:
- 在了解症状体验和机制方面的科学差距阻碍了有效的干预.
- 个性化方法对于改善患者的生活质量和健康结果至关重要.
研究的目的:
- 描述症状表型的发展和识别的分析方法.
- 在精确的健康症状科学中审查常见和新兴的生物标志物发现方法.
- 讨论这些方法对促进症状管理的影响.
主要方法:
- 综合同行评审的研究,评论文章和专家知识.
- 提供了生物标志物发现方法及其相关性的广泛概述.
- 专注于对精确健康症状科学的影响.
主要成果:
- 对症状表型发展和识别的方法进行了审查.
- 描述的常见 (基因组,表观基因组等) 和新兴产品 (可穿戴设备,多基因风险评分等). 生物标志物发现方法.
- 强调生物标志物对于风险预测,查,监测和治疗反应的有用性.
结论:
- 虽然在瘤学中已经展示了示例性的方法,但在各种疾病中都适用.
- 症状生物标志物的发现是复杂和不断发展的,需要跨学科的团队.
- 症状科学家准备领导精确的健康症状科学,以减少症状负担.
相关概念视频
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
37
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
37
Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
66
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
66
Serum Laboratory Studies, Stool Test, Breath Test
234
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
234
Errors occurring during blood pressure monitoring
565
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
565


