改变的胰岛功能连接与失眠中的认知灵活性相关
Shiyan Yang1,2, Yuhan Fan1,2, Zilu Zhang2,3
1Faculty of Psychology, Sleep and NeuroImaging Center, Southwest University, Chongqing, 400715, China.
Brain topography
|April 23, 2025
概括
失眠会影响认知灵活性,因为它会改变大脑活动和连接能力,特别是在右脑岛和补充运动区域. 特定的神经通路与认知灵活性的不同方面有关,对中侧叶片可能是不眠症患者独特的.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 睡眠医学 睡眠医学
背景情况:
- 失眠与认知缺陷有关,包括认知灵活性受损.
- 在失眠中认知灵活性的神经支仍然不完全理解.
研究的目的:
- 研究失眠患者认知灵活性受损的神经机制.
- 使用休息状态fMRI检查失眠严重程度,大脑活动和认知灵活性之间的关系.
主要方法:
- 使用了休息状态功能磁共振成像 (fMRI).
- 分析了低频波动的分数振幅 (fALFF) 和功能连接 (FC).
- 认知灵活性库存 (CFI) 用于评估认知灵活性.
主要成果:
- 失眠的严重程度对认知灵活性的控制子维度产生了负面影响.
- 右半岛与整体认知灵活性有显著的关联.
- 胰岛与其他大脑区域 (如STG,前) 之间的功能连接与认知灵活性得分相关.
- 特定的神经通路涉及补充运动区域和准中心叶片与不同的认知灵活性子维度相关.
结论:
- 认知灵活性的不同次维度由不同的神经通路支持.
- 副中心叶片可能代表大脑区域,在失眠患者中特别受影响,涉及认知灵活性.
- 这些发现突出了失眠对认知灵活性神经基础的影响,并提出了潜在的治疗目标.
相关概念视频
Insomnia
75
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Multiple factors contribute...
75
Insufficient Sleep and Sleep Deprivation
118
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
118
Management of Insomnia
185
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
185
Altered States of Awareness
114
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
114


