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Updated: May 10, 2025

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction
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Published on: January 9, 2015

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AAA+ SPATA5复合体的冷EM结构及其在人类细胞质60S前成熟中的作用

Yuhao Dai1,2, Damu Wu1,2, Ningning Li1

  • 1State Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking University, Beijing, China.

Nature communications
|April 23, 2025
PubMed
概括

人类SPATA5蛋白质复合物通过释放60S前颗粒的因子来帮助核糖体组装. 一个冷EM结构揭示了人类特异性相互作用,为核糖体生物发生提供了治疗点.

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