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Updated: May 10, 2025

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人类GABA载体3抑制的分子基础

Ravi Yadav1,2, Gye Won Han1, Cornelius Gati3,4,5

  • 1The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.

Nature communications
|April 23, 2025
PubMed
概括

研究人员揭示了SNAP-5114如何非竞争性地抑制玛-氨基黄油酸 (GABA) 载体3 (GAT3). 结构和功能研究为设计用于神经系统疾病的新型GAT3向药物提供了基础.

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